⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729648 | 1.00 | — | — | |
| SCHEMBL103038 | 0.74 | — | — | |
| SCHEMBL13265536 | 0.74 | — | — | |
| SCHEMBL31314223 | 0.74 | — | — | |
| SCHEMBL16121946 | 0.74 | — | — | |
| SCHEMBL24542697 | 0.72 | NOS2 (0.39) | — | |
| SCHEMBL802374 | 0.71 | — | — | |
| SCHEMBL12647312 | 0.70 | PTGS1 (0.34) | — | |
| SCHEMBL11634390 | 0.70 | NOS3 (0.38) | — | |
| SCHEMBL24857294 | 0.69 | NOS3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667562-B1 | Charge injection barrier for positive charging organic photoconductor | HEWLETT PACKARD CO (US) | 2001-03-21 | — | — | EP | claimed |
| US-20210171529-A1 | HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE | AMGEN INC. | 2021-06-10 | — | — | US | disclosed |
| CN-112930347-A | Inhibitors of KEAP1-Nrf2 protein-protein interactions | 詹森药业有限公司 | 2021-06-08 | — | — | CN | disclosed |
| US-9723840-B2 | 1-(pyridazin-3-yl)-imidazolidin-2-one derivatives as herbicides | SYNGENTA LIMITED (GB) | 2017-08-08 | — | — | US | disclosed |
| US-20160262395-A1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | EMORY UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| US-5556730-A | Charge injection barrier for positive charging organic photoconductor | HEWLETT-PACKARD COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5476604-A | Crosslinked binder of polyvinyl alcohol | HEWLETT-PACKARD COMPANY (US) | 1995-12-19 | — | — | US | disclosed |