Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450599 | 0.95 | — | — | |
| SCHEMBL5610168 | 0.72 | MAPT (0.35) | MAPTTHRBRECQLKMT2AMEN1 | |
| SCHEMBL12154897 | 0.68 | SMN1; SMN2 (0.34) | MAPTTHRBRECQLKMT2AMEN1 | |
| SCHEMBL10995790 | 0.68 | — | — | |
| SCHEMBL8686729 | 0.67 | — | — | |
| SCHEMBL592856 | 0.67 | — | — | |
| SCHEMBL6006346 | 0.66 | CES2 (0.40) | MAPTRECQLKMT2AMEN1KDM4E | |
| SCHEMBL17971494 | 0.65 | TRIM24 (0.54) | KMT2AMAOAMAOBTRIM24TRIM33 | |
| SCHEMBL33935 | 0.65 | — | — | |
| SCHEMBL689737 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000086569-A | CYCLOHEPTENONE DERIVATIVE AND ITS PRODUCTION, AND PRODUCTION OF CYCLOHEPTOIMIDAZOLE DERIVATIVE USING THE SAME | KOTOBUKI SEIYAKU KK | 2000-03-28 | — | — | JP | disclosed |