Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.84 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039820 | 0.91 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8037672 | 0.89 | PTGS2 (0.67) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8033665 | 0.88 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL8023471 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8033574 | 0.85 | PTGS2 (0.74) | PTGS2CYP2C9 | |
| SCHEMBL8033128 | 0.84 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL8036564 | 0.84 | PTGS2 (0.86) | PTGS2PTGS1 | |
| SCHEMBL8033132 | 0.84 | PTGS2 (0.81) | PTGS2 | |
| SCHEMBL8034991 | 0.83 | PTGS2 (0.83) | PTGS2 | |
| SCHEMBL6511278 | 0.82 | PTGS2 (0.70) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | claimed |
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | disclosed |