SCHEMBL8024018

SCHEMBL8024018

Cc1cc(N)c(O)c([N+](=O)[O-])c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 4/20 0.74
CA9 Q16790 6/20 0.59
CA12 O43570 5/20 0.59
CA2 P00918 5/20 0.59
CA1 P00915 4/20 0.59
GAA P10253 2/20 0.59
NSD2 O96028 1/20 0.59
PLCG1 P19174 1/20 0.59
DNMT1 P26358 1/20 0.59
CASP6 P55212 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TSHR P16473 2/20 0.56
CA4 P22748 1/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322531 0.86 GPR35 (1.00) GPR35CA9CA12CA2CA1
SCHEMBL28817836 0.84 GPR35 (0.95) GPR35CA9CA12CA2CA1
SCHEMBL28239608 0.81 GPR35 (0.59) GPR35CA9CA12CA2CA1
SCHEMBL9310524 0.80 GPR35 (0.69) GPR35CA9CA12CA2CA1
SCHEMBL7786697 0.80 TSHR (0.60) GPR35L3MBTL1TSHRALDH1A1MAPT
SCHEMBL13681604 0.80 GPR35 (0.80) GPR35L3MBTL1TSHRALDH1A1MAPT
SCHEMBL4847900 0.80 GPR35 (0.80) GPR35CA9CA12CA2CA1
SCHEMBL259813 0.80 TSHR (0.60) GPR35L3MBTL1TSHRALDH1A1MAPT
SCHEMBL10749719 0.80 GPR35 (0.80) GPR35GAATSHRALDH1A1MAPT
Hydrochloric Acid SCHEMBL27931552 0.79 GPR35 (0.58) GPR35CA9CA12CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4333730-A HAIR DYES SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-08 US claimed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US claimed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US claimed
EP-1756355-B1 METHOD FOR THE REACTIVE COLORATION OF LEATHER BASF SE (DE) 2010-08-25 EP disclosed
US-6045593-A Acid yellow dye and method for using same CK HOLDING CORPORATION, A DELAWARE CORPORATION 2000-04-04 US disclosed
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0944674-A1 ACID YELLOW DYE AND METHOD FOR USING SAME CROMPTON & KNOWLES CORPORATION (US) 1999-09-29 EP disclosed
US-5874095-A PHARMACEUTICAL ACTIVE MATERIAL, NON-IONIC CROSSLINKED POLYACRYLAMIDE HAVING A MOLECULAR WEIGHT OF FROM 1,000,000 TO 30,000,000, THE POLYACRYLAMIDE BEING PREDISPERSED IN A WATER-IMMISCIBLE OIL CONTAINING A SURFACTANT RICHARDSON-VICKS INC. (US) 1999-02-23 US disclosed
US-5874547-A REACTING A PRIMARY AROMATIC AMINE WITH DIAZOTIZING AGENT IN SOLUTION; AZO DYES CROMPTON & KNOWLES CORPORATION (US) 1999-02-23 US disclosed
US-5871554-A OIL SOLUBLE POLYMERS HAVING DISPERSANT AND ANTIOXIDANT PROPERTIES IN OLEAGINOUS COMPOSITIONS, INCLUDING FUEL AND LUBRICATING OILS EXXON CHEMICAL PATENTS INC. (US) 1999-02-16 US disclosed
WO-1998022537-A1 ACID YELLOW DYE AND METHOD FOR USING SAME CROMPTON & KNOWLES CORPORATION (US) 1998-05-28 WO disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4068085-A YELLOW AND RED ON POLYESTERS AND ACRYLICS CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4052374-A UNSYMMETRICAL 1:2-CHROMIUM COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4033943-A Fiber reactive water soluble 2,4,6-triamino, 3-cyano pyridine-(5) azo dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-3994872-A SOLUBILITY CIBA-GEIGY CORPORATION (US) 1976-11-30 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3970615-A Unsymmetrical mono-sulfo containing chromium complexes of azo dyes CIBA-GEIGY CORPORATION (US) 1976-07-20 US disclosed