SCHEMBL8024030

SCHEMBL8024030

O=C(O)CCNC(CO)(CO)CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
EGLN1 Q9GZT9 2/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
ECE1 P42892 1/20 0.37
CAMK2A Q9UQM7 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
KDM4E B2RXH2 2/20 0.33
KDM5C P41229 2/20 0.33
PHF8 Q9UPP1 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
TSHR P16473 2/20 0.33
KDM6B O15054 1/20 0.33
FOLH1 Q04609 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
PRMT1 Q99873 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28419097 0.89 ECE1 (0.38) LMNAEGLN1ALKBH5SUCNR1ECE1
SCHEMBL12227728 0.87 FFAR3 (0.37) LMNAEGLN1ALKBH5SUCNR1ECE1
SCHEMBL10989261 0.82 PRMT1 (0.52) LMNASLC22A6TSHRGPR84NFKB1
Succinic Acid SCHEMBL25211031 0.80 EGLN1 (0.45) LMNAEGLN1ALKBH5SUCNR1CAMK2A
SCHEMBL21787660 0.78
Bicarbonate SCHEMBL20591234 0.77 HTT (0.31)
SCHEMBL12227932 0.76 NAALAD2 (0.36) LMNAEGLN1ALKBH5SUCNR1ECE1
SCHEMBL12227731 0.76 EGLN1 (0.41) LMNAEGLN1ALKBH5SUCNR1ECE1
SCHEMBL42019 0.76 LDHA (0.37) LMNAEGLN1ALKBH5SUCNR1LDHA
SCHEMBL412337 0.76 LDHA (0.37) LMNAEGLN1ALKBH5SUCNR1LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4268981-A1 AQUEOUS DISPERSION AGC INC. (JP) 2023-11-01 EP claimed
WO-2022138483-A1 AQUEOUS DISPERSION AGC株式会社 2022-06-30 WO claimed
WO-2025033551-A1 AQUEOUS DISPERSION AND METHOD FOR PRODUCING LAMINATE AGC株式会社 2025-02-13 WO disclosed
EP-4268981-A1 AQUEOUS DISPERSION AGC INC. (JP) 2023-11-01 EP disclosed
WO-2022138483-A1 AQUEOUS DISPERSION AGC株式会社 2022-06-30 WO disclosed
EP-3500552-A2 PH-RESPONSIVE LIPIDS University Of Kwazulu-Natal (ZA) 2019-06-26 EP disclosed
WO-2018033883-A2 PH-RESPONSIVE LIPIDS UNIVERSITY OF KWAZULU NATAL (ZA) 2018-02-22 WO disclosed
US-8334402-B2 Biological buffers with wide buffering ranges TPAT IP LLC 2012-12-18 US disclosed
US-8034951-B2 Biological buffers with wide buffering ranges TPAT IP LLC 2011-10-11 US disclosed
US-20110137076-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2011-06-09 US disclosed
US-7939659-B2 Biological buffers with wide buffering ranges TPAT IP LLC 2011-05-10 US disclosed
US-20100190993-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2010-07-29 US disclosed
US-20100099868-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2010-04-22 US disclosed
EP-0569132-B1 Improvements in radiolabelling ANORMED INC (CA) 2000-03-01 EP disclosed
US-5350837-A Complexes with 99m Tc suitable for radiolabelling monoclonal antibodies or other macro molecules JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1994-09-27 US disclosed
EP-0569132-A1 Improvements in radiolabelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1993-11-10 EP disclosed
US-4543216-A REACTING A VINYL BENZYL HALIDE WITH AN AMINO ACID OR AMINO SULFONIC ACID NIPPON PAINT CO., LTD. (JP) 1985-09-24 US disclosed
US-4452746-A TO MODIFY PROPERTIES OF HIGH MOLECULAR WEIGHT COMPOUNDS NIPPON PAINT CO., LTD. (JP) 1984-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099868-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP LMNA 1639/4885EGLN1 3736/4885ALKBH5 2465/4885
US-20100190993-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP LMNA 1639/4885EGLN1 3736/4885ALKBH5 2465/4885
US-20110137076-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP LMNA 1639/4885EGLN1 3736/4885ALKBH5 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.