Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026485 | 0.88 | ALDH1A1 (0.43) | ADRB2ADRB1ADRB3CHRNB2CHRNB4 | |
| SCHEMBL8914496 | 0.83 | NPC1 (0.48) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL7870952 | 0.83 | LIG1 (0.51) | LIG1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL8024675 | 0.82 | MEN1 (0.41) | MEN1KMT2AGAATSHRALDH1A1 | |
| SCHEMBL6394825 | 0.78 | LIG1 (0.46) | LIG1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL11409674 | 0.78 | CYP3A4 (0.46) | MEN1KMT2APOLBGAATSHR | |
| SCHEMBL11121483 | 0.76 | LIG1 (0.60) | LIG1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL8922614 | 0.75 | LIG1 (0.56) | LIG1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10611398 | 0.75 | LIG1 (0.58) | LIG1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL2831629 | 0.74 | MAPT (0.49) | ADRB2ADRB1ADRB3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153272-A | POLYMER SURFACE IN CONTACT WITH A LIQUID CRYSTAL MEDIUM IS EXPOSED TO POLARIZED LIGHT, WHEREBY A COVALENTLY BOUND ANISOTROPIC COMPONENT OF THE POLYMER SURFACE ALIGNS IN RESPONSE TO THE POLARIZED LIGHT | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0387059-B1 | Process of aligning liquid crystal media | HERCULES INC (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5589100-A | LIQUID CRYSTAL DISPLAY SUBSTRATES WITH ARYLAZO OR POLYARYLAZO DYES | HERCULES INCORPORATED (US) | 1996-12-31 | — | — | US | disclosed |
| US-5389285-A | Liquid crystal coupled dichroic dyes | HERCULES INCORPORATED (US) | 1995-02-14 | — | — | US | disclosed |
| US-5326865-A | Arylazo and poly(arylazo) dyes having at least one core radical selected from naphthyl or anthracyl and having at least one 2,3-dihydro-1,3-dialkyl perimidine substituent | HERCULES INCORPORATED (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0460504-B1 | Dichroic azo dyes | HERCULES INC (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5097029-A | Hydrolysis, alkylation, intermediates for azo dyes | HERCULES INCORPORATED (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0460504-A1 | Dichroic azo dyes | HERCULES INCORPORATED (US) | 1991-12-11 | — | — | EP | disclosed |
| US-5032009-A | Polarized light exposure | HERCULES INCORPORATED (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0432735-A2 | Liquid crystal coupled dichroic dyes | HERCULES INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4974941-A | Process of aligning and realigning liquid crystal media | HERCULES INCORPORATED (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0387059-A2 | Process of aligning liquid crystal media | HERCULES INCORPORATED (US) | 1990-09-12 | — | — | EP | disclosed |