Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024089 | 0.83 | LIG1 (0.42) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29023341 | 0.81 | RXRA (0.48) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2831629 | 0.80 | MAPT (0.49) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2364296 | 0.80 | MAPT (0.49) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6394828 | 0.80 | ALDH1A1 (0.42) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8723330 | 0.79 | THRB (0.45) | NPC1RAB9ALPAR1LPAR5MAPK14 | |
| SCHEMBL8727994 | 0.79 | THRB (0.45) | NPC1RAB9ALPAR1LPAR5MAPK14 | |
| Cyanide SCHEMBL30294043 | 0.79 | RXRA (0.46) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8026485 | 0.79 | ALDH1A1 (0.43) | NPC1RAB9ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11514420 | 0.79 | NPC1 (0.65) | NPC1RAB9ALPAR1LPAR5ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5601884-A | COMPRISING A LIQUID CRYSTAL OLIGOMER; HEAT RESISTANCE, CHEMICAL RESISTANCE; STABILITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0678567-A1 | Retardation film and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |