Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546094 | 0.77 | ESR2 (0.48) | ESR2CYP1A2MEN1KMT2AAPAF1 | |
| SCHEMBL1961187 | 0.77 | TP53 (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL21495096 | 0.77 | TP53 (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL38142 | 0.76 | ACP3 (0.39) | MEN1KMT2ALMNAMAPTBLM | |
| SCHEMBL22445608 | 0.76 | ACP3 (0.39) | MEN1KMT2ALMNAMAPTBLM | |
| SCHEMBL3246785 | 0.76 | ACP3 (0.44) | CYP1A2PTGS2ACP3ALDH1A1MAPK1 | |
| SCHEMBL20551407 | 0.74 | MDM2 (0.39) | LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2932458 | 0.74 | MDM2 (0.39) | LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL846656 | 0.74 | GABRA1 (0.33) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL8058289 | 0.73 | TAAR1 (0.46) | ESR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979079-A1 | USE OF TETRAHYDROPYRIDINE DERIVATIVES TO PREPARE MEDICINES FOR TREATING DISEASES CAUSING DEMYELINATION | SANOFI-SYNTHELABO (FR) | 2000-02-16 | — | — | EP | disclosed |
| EP-0950053-A1 | USE OF BENZOYLALKYL-1,2,3,6-TETRAHYDROPYRIDINS | SANOFI (FR) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998048802-A1 | USE OF TETRAHYDROPYRIDINE DERIVATIVES TO PREPARE MEDICINES FOR TREATING DISEASES CAUSING DEMYELINATION | SANOFI-SYNTHELABO (FR) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998028274-A1 | USE OF BENZOYLALKYL-1,2,3,6-TETRAHYDROPYRIDINS | SANOFI (FR) | 1998-07-02 | — | — | WO | disclosed |