Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550123 | 0.84 | MMP8 (0.53) | MMP8PIN1LMNACYP1A2CYP2D6 | |
| SCHEMBL28024406 | 0.83 | ATM (0.51) | MMP8LMNACYP1A2CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL28024368 | 0.82 | ATM (0.50) | LMNACYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL2683020 | 0.82 | PGR (0.50) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL30337118 | 0.82 | PGR (0.50) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL629045 | 0.82 | PGR (0.50) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL627946 | 0.80 | PGR (0.49) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL890238 | 0.80 | PGR (0.49) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL901698 | 0.80 | PGR (0.49) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL14816808 | 0.80 | PGR (0.49) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000055112-A1 | ANTI-VIRAL COMPOUNDS | LOVESGROVE RESEARCH LIMITED (GB) | 2000-09-21 | — | — | WO | disclosed |
| US-4486179-A | ESTERS OF SYRINGIC ACID AS ANTICARIES AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1984-12-04 | — | — | US | disclosed |