Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777073 | 0.93 | ADRB2 (0.44) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7775740 | 0.90 | ADRB2 (0.43) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL8009962 | 0.89 | NPC1 (0.49) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7770715 | 0.87 | NPC1 (0.51) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7776932 | 0.86 | NPC1 (0.52) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7775414 | 0.86 | NPC1 (0.52) | NPC1MAPTRAB9ASMN1; SMN2POLB | |
| SCHEMBL7619158 | 0.86 | NPC1 (0.52) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL8026374 | 0.86 | NPC1 (0.52) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7775472 | 0.85 | ADRB2 (0.44) | NPC1MAPTRAB9AADRB2ADRB1 | |
| SCHEMBL7775451 | 0.85 | NPC1 (0.49) | NPC1MAPTRAB9AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040411-A | Low glass temperature organosiloxanes | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2000-03-21 | — | — | US | disclosed |