Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053232 | 0.83 | PDE4B (0.45) | PDE4BPDE4D | |
| SCHEMBL15906102 | 0.81 | PDE4B (0.49) | PDE4BPDE4D | |
| SCHEMBL8028328 | 0.81 | PDE4B (0.41) | PDE4BPDE4D | |
| SCHEMBL8071898 | 0.81 | PDE4B (0.56) | PDE4BPDE4D | |
| SCHEMBL3795584 | 0.80 | PDE4B (0.67) | PDE4BPDE4D | |
| SCHEMBL11996294 | 0.80 | PDE4B (0.46) | PDE4BPDE4D | |
| SCHEMBL8071504 | 0.79 | CXCR4 (0.46) | PDE4B | |
| SCHEMBL8070648 | 0.77 | PDE4B (0.42) | PDE4BPDE4D | |
| SCHEMBL3785787 | 0.77 | PDE4B (0.65) | PDE4BPDE4D | |
| SCHEMBL8066164 | 0.76 | PDE4B (0.44) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009067621-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |