Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197707 | 0.83 | CYP2D6 (0.64) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL3894545 | 0.83 | CYP2D6 (0.64) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL6729778 | 0.83 | SLC6A9 (0.64) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL12323998 | 0.83 | SLC6A2 (0.48) | SLC6A4HRH3HTR2AHRH1SLC6A2 | |
| SCHEMBL7169436 | 0.81 | SLC6A4 (0.52) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| Hydrochloric Acid SCHEMBL7320057 | 0.81 | SLC6A4 (0.56) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL8026016 | 0.79 | SLC6A4 (0.51) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL9995405 | 0.79 | SLC6A4 (0.67) | SLC6A4HRH3SLC6A2 | |
| SCHEMBL8022173 | 0.79 | SLC6A4 (0.54) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL7158810 | 0.79 | SLC6A4 (0.73) | SLC6A4HRH3HTR2AHRH1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058262-A1 | STEREOSPECIFIC METHOD FOR PREPARING TOMOXETINE AND INTERMEDIATES THEREOF | ELI LILLY AND COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |