Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17200847 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MAPK1MEN1CYP1A2KMT2A | |
| SCHEMBL2448213 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPK1SMN1; SMN2CA12CA2 | |
| SCHEMBL24983 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPK1SMN1; SMN2CA12CA2 | |
| SCHEMBL1510123 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL610112 | 0.83 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL2960 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPK1NPC1RAB9ANFKB1 | |
| SCHEMBL2753352 | 0.80 | IDO1 (0.32) | ALDH1A1MAPK1METAP2 | |
| SCHEMBL5357790 | 0.78 | IDO1 (0.42) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL509984 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL147390 | 0.77 | RAB9A (0.36) | ALDH1A1NPC1RAB9ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1909908-A | Pyrazolo [1, 5-a ] pyrimidin-7-yl-amine derivatives for the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2007-02-07 | — | — | CN | claimed |
| EP-0805795-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022965-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1996-08-01 | — | — | WO | claimed |
| CN-116157399-A | Novel compound for capping layer and organic light-emitting element comprising same | 东进世美肯株式会社 | 2023-05-23 | — | — | CN | disclosed |
| CN-109187406-A | A kind of differential protein detection method of 1- (4- bromophenyl) -5- phenyl -1H- triazole and serum effect | 海南师范大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-109046463-A | Bidentate azepine Cabbeen Mn catalyst and preparation method thereof and alkylation synthesis application | 中山大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-106892872-A | A kind of synthetic method of 2- (4- bromophenyls) -4- xenyl -6- phenyl pyrimidines | 西安瑞联新材料股份有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-104736541-B | Novel compound and organic electroluminescent element comprising same | 株式会社斗山 | 2017-05-31 | — | — | CN | disclosed |
| CN-106588796-A | Aromatic primary diamine containing triaryl s-triazine structure and ether bond and preparation method thereof | 大连理工大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-106458961-A | Organic compound and organic electroluminescent element comprising same | 株式会社斗山 | 2017-02-22 | — | — | CN | disclosed |
| CN-103732719-B | The manufacture method of phosphorescent light-emitting materials, phosphorescent light-emitting materials and phosphorescence luminous element | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORP. (JP) | 2015-12-02 | — | — | CN | disclosed |
| CN-1909908-A | Pyrazolo [1, 5-a ] pyrimidin-7-yl-amine derivatives for the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2007-02-07 | — | — | CN | disclosed |
| CN-1708550-A | Flame-resistant vinyl chloride based resin composition and formed product therefrom | MITSUBISHI PLASTICS INC (JP) | 2005-12-14 | — | — | CN | disclosed |
| US-6159973-A | Aromatic amides, their preparation process, the compositions containing them and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2000-12-12 | — | — | US | disclosed |
| EP-0805795-B1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO SA (FR) | 2000-08-23 | — | — | EP | disclosed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0805795-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022965-A1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1996-08-01 | — | — | WO | disclosed |
| US-5527816-A | AGRICULTURAL USE | ROHM AND HAAS COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0104863-B1 | LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |