SCHEMBL8024768

SCHEMBL8024768

C=C(C)C(=O)NCCOC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.64
DNM1 Q05193 1/20 0.50
TSHR P16473 3/20 0.47
EPHX2 P34913 4/20 0.47
PAM P19021 2/20 0.46
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
MAPT P10636 1/20 0.44
PLA2G2A P14555 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
NAAA Q02083 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20541917 0.87 DGKA (0.43) DGKADNM1TSHREPHX2ALDH1A1
SCHEMBL20379689 0.85 ADRA2A (0.41) DGKATSHRMAPTALDH1A1
SCHEMBL10912888 0.82 EPHX2 (0.50) DGKADNM1EPHX2
SCHEMBL10080728 0.81 EPHX2 (0.50) DGKATSHREPHX2ALDH1A1
SCHEMBL20276199 0.81 DGKA (0.72) DGKADNM1TSHRPAMPRSS1
SCHEMBL20276146 0.81 DGKA (0.72) DGKADNM1TSHRPAMPRSS1
SCHEMBL20276263 0.81 DGKA (0.72) DGKADNM1TSHRPAMPRSS1
SCHEMBL9769723 0.81 DGKA (0.72) DGKADNM1TSHRPAMPRSS1
SCHEMBL20276150 0.81 DGKA (0.72) DGKADNM1TSHRPAMPRSS1
SCHEMBL20276157 0.81 DGKA (0.72) DGKADNM1TSHRPAMPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080480-A THERMOPLASTIC RESIN HOMOPOLYMERS OR COPOLYMERS FROM RADICAL POLYMERIZATION TOYO INK MANUFACTURING CO., LTD. (JP) 2000-06-27 US disclosed
EP-0852614-B1 DELAYED-TACK ADHESIVE COMPOSITION KAO CORP (JP) 2000-03-01 EP disclosed
EP-0852614-A1 DELAYED-TACK ADHESIVE COMPOSITION Kao Corporation (JP) 1998-07-15 EP disclosed
WO-1997012010-A1 DELAYED-TACK ADHESIVE COMPOSITION KAO CORPORATION (JP) 1997-04-03 WO disclosed