Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11012476 | 0.91 | TSHR (0.65) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL8813261 | 0.83 | TSHR (0.70) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL10958389 | 0.83 | TSHR (0.70) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL28971642 | 0.83 | TSHR (0.70) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL509040 | 0.83 | TSHR (0.46) | TSHRLMNAALDH1A1 | |
| SCHEMBL27953228 | 0.83 | TSHR (0.88) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL14975 | 0.83 | TSHR (0.88) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL7923176 | 0.82 | ALDH1A1 (0.54) | TSHRLMNAALDH1A1 | |
| SCHEMBL642929 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL29195604 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048933-A | HYDROGENATED BLOCK POLYMERS AND PEROXIDE CROSSLINKING AGENTS | RIKEN VINYL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0770645-B1 | Thermoplastic elastomeric resin composition and a process for the preparation thereof | RIKEN VINYL IND (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5929165-A | HEAT TREATING POLYMERIC BLOCKS COMPOSED MAINLY OF A VINYL AROMATIC COMPOUND AND AT LEAST ONE POLYMERIC BLOCK COMPOSED MAINLY OF A CONJUGATED DIENE COMPOUND WITH A PEROXY CROSSLINKER | RIKEN VINYL INDUSTRY CO., LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0770645-A2 | Thermoplastic elastomeric resin composition and a process for the preparation thereof | RIKEN VINYL INDUSTRY CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |