Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030988 | 0.89 | KDM4E (0.53) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8037202 | 0.89 | KDM4E (0.46) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8031033 | 0.87 | KDM4E (0.48) | KDM4ERAB9AHSD17B10TSHRPOLB | |
| SCHEMBL8036404 | 0.87 | CYP1A2 (0.43) | RAB9ATP53TSHRPOLBCYP1A2 | |
| SCHEMBL8034096 | 0.86 | KDM4E (0.50) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8021662 | 0.86 | KDM4E (0.50) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8031451 | 0.82 | KDM4E (0.46) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8037293 | 0.81 | LMNA (0.49) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8040695 | 0.81 | CNR1 (0.46) | KDM4ERAB9ATP53HSD17B10TSHR | |
| SCHEMBL8031450 | 0.81 | CYP1A2 (0.47) | KDM4ERAB9ATP53HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |