Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036259 | 0.88 | NR1H4 (0.39) | CYP1A2POLBMAPTLMNAALDH1A1 | |
| SCHEMBL8032185 | 0.88 | LMNA (0.45) | CYP1A2POLBMAPTLMNATP53 | |
| SCHEMBL8024872 | 0.87 | KDM4E (0.48) | CYP1A2POLBMAPTLMNATP53 | |
| SCHEMBL8038397 | 0.85 | TARBP2 (0.49) | CYP1A2POLBMAPTLMNATP53 | |
| SCHEMBL8034254 | 0.83 | LMNA (0.42) | CYP1A2POLBMAPTLMNATP53 | |
| SCHEMBL8034697 | 0.80 | MAPT (0.40) | CYP1A2POLBMAPTLMNATP53 | |
| SCHEMBL4007701 | 0.79 | CTRC (0.41) | CYP1A2POLBMAPTTP53ALDH1A1 | |
| SCHEMBL8031450 | 0.77 | CYP1A2 (0.47) | CYP1A2POLBMAPTLMNATP53 | |
| SCHEMBL8034649 | 0.77 | NR1H4 (0.40) | CYP1A2POLBMAPTLMNAALDH1A1 | |
| SCHEMBL8031033 | 0.77 | KDM4E (0.48) | CYP1A2POLBMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |