Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850904 | 0.89 | ESR2 (0.35) | DGAT1ESR2SOAT1 | |
| SCHEMBL9136523 | 0.89 | OPRL1 (0.34) | ESR2OPRL1 | |
| SCHEMBL8024986 | 0.89 | ESR2 (0.35) | DGAT1ESR2SOAT1 | |
| SCHEMBL8034778 | 0.87 | — | — | |
| SCHEMBL8034786 | 0.87 | — | — | |
| SCHEMBL8034782 | 0.87 | — | — | |
| SCHEMBL19850841 | 0.87 | ESR2 (0.35) | DGAT1ESR2SOAT1 | |
| SCHEMBL19844724 | 0.86 | SLC6A3 (0.35) | DGAT1ESR2OPRL1SOAT1 | |
| SCHEMBL6141758 | 0.85 | DGAT1 (0.33) | DGAT1ESR2OPRL1SOAT1 | |
| SCHEMBL6142164 | 0.85 | ESR2 (0.31) | ESR2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497176-B1 | Four rings compounds and liquid crystal mixtures containing them | MERCK PATENT GMBH (DE) | 2000-04-05 | — | — | EP | disclosed |
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0497176-A2 | Four rings compounds and liquid crystal mixtures containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |