Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 7/20 | 0.40 |
| ▸ | METAP1 | P53582 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376615 | 0.88 | EPHX1 (0.52) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL1157633 | 0.83 | ARG1 (0.60) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL13659832 | 0.83 | NOS2 (0.44) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL1157636 | 0.83 | ARG1 (0.60) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL8084363 | 0.83 | ARG1 (0.60) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL8022170 | 0.82 | — | — | |
| SCHEMBL11114575 | 0.82 | — | — | |
| SCHEMBL24154514 | 0.81 | NOS2 (0.47) | NOS2NOS1NOS3EPHX1TDP1 | |
| SCHEMBL28472089 | 0.81 | ARG1 (0.58) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL8024937 | 0.81 | ARG1 (0.40) | NOS2NOS1NOS3ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406265-B1 | COMPLEXES OF VIRAL-BASED THERAPEUTIC AGENTS AND MODIFIED POLY(BETA-AMINO ESTERS) | SAGETIS BIOTECH SL (ES) | 2020-07-29 | — | — | EP | disclosed |
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |