Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17395812 | 0.84 | TSHR (0.44) | KMT2AMEN1HCAR3TSHRHTT | |
| SCHEMBL14097842 | 0.80 | ESR1 (0.43) | KMT2AMGLL | |
| SCHEMBL27595482 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1HCAR3TSHRALDH1A1 | |
| SCHEMBL2783327 | 0.80 | ALDH1A1 (0.48) | KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL28263198 | 0.80 | SLC6A2 (0.46) | ALDH1A1MGLLHPGD | |
| SCHEMBL11249479 | 0.78 | SLC6A2 (0.45) | ALDH1A1MGLLHPGD | |
| SCHEMBL2886641 | 0.78 | RAB9A (0.69) | KMT2AMEN1TSHRALDH1A1HPGD | |
| SCHEMBL5070934 | 0.77 | ALDH1A1 (0.43) | KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL24763632 | 0.77 | SMN1; SMN2 (0.50) | TSHRHTTALDH1A1HPGD | |
| SCHEMBL2184433 | 0.77 | SMN1; SMN2 (0.50) | TSHRHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816356-B1 | 1-(2-(1-piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazole derivatives and their pharmaceutical use | LILLY CO ELI (GB) | 2000-11-02 | — | — | EP | disclosed |
| US-6075039-A | 5HT receptor binding benzimidazolylpiperidines | ELI LILLY AND COMPANY LIMITED (GB) | 2000-06-13 | — | — | US | disclosed |
| EP-0816356-A1 | 1-(2-(1-piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazole derivatives and their pharmaceutical use | ELI LILLY AND COMPANY LIMITED (GB) | 1998-01-07 | — | — | EP | disclosed |