Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024842 | 0.90 | MAOA (0.43) | MAOABRD4 | |
| SCHEMBL1011843 | 0.77 | MAOA (0.43) | MAOAPRCP | |
| SCHEMBL8028587 | 0.77 | MAOA (0.45) | MAOAPLAUASIC3BRD4PRCP | |
| SCHEMBL8026602 | 0.73 | DRD2 (0.47) | — | |
| SCHEMBL8026339 | 0.73 | CHEK1 (0.46) | MAOAPLAU | |
| SCHEMBL8025234 | 0.73 | MAOA (0.49) | MAOAPLAUASIC3PRCP | |
| SCHEMBL8012551 | 0.72 | BRD4 (0.55) | BRD4 | |
| SCHEMBL8030414 | 0.72 | MAOA (0.46) | MAOA | |
| SCHEMBL8023234 | 0.72 | MAOA (0.48) | MAOAPLAUASIC3PRCP | |
| SCHEMBL8023881 | 0.72 | MAOA (0.57) | MAOAPLAUASIC3PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |