Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532848 | 0.91 | FKBP1A (0.38) | FKBP1AMAPTPKMALDH1A1LMNA | |
| SCHEMBL15432009 | 0.82 | MMP2 (0.46) | FKBP1A | |
| SCHEMBL26427037 | 0.82 | MMP2 (0.46) | FKBP1A | |
| SCHEMBL7054243 | 0.81 | PARP1 (0.43) | FKBP1AALDH1A1LMNAKMT2A | |
| SCHEMBL6541621 | 0.81 | PARP1 (0.43) | FKBP1AALDH1A1LMNAKMT2A | |
| SCHEMBL7056396 | 0.81 | PARP1 (0.43) | FKBP1AALDH1A1LMNAKMT2A | |
| SCHEMBL3316200 | 0.81 | MAPT (0.39) | FKBP1AMAPTPKMALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29024753 | 0.81 | MMP2 (0.45) | FKBP1A | |
| SCHEMBL7352757 | 0.80 | POLB (0.40) | FKBP1AMAPTPKMALDH1A1LMNA | |
| SCHEMBL6729877 | 0.79 | MAPT (0.36) | FKBP1AMAPTPKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968201-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998035951-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-20 | — | — | WO | disclosed |