Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026802 | 0.89 | CDK1 (0.50) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL8705066 | 0.86 | HTT (0.51) | EGFRGALR3NR2F2RAB9ALMNA | |
| SCHEMBL11110616 | 0.79 | EGFR (0.54) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL8024318 | 0.77 | EGFR (0.51) | EGFRLMNAHTTMAPK1 | |
| SCHEMBL8025185 | 0.76 | PRMT1 (0.48) | EGFRGALR3LMNAHTTKMT2A | |
| SCHEMBL9403592 | 0.75 | GALR3 (0.55) | EGFRGALR3NR2F2RAB9ALMNA | |
| SCHEMBL8485751 | 0.75 | HTT (0.51) | EGFRGALR3RAB9ALMNAHTT | |
| SCHEMBL9037262 | 0.74 | GALR3 (0.59) | EGFRGALR3NR2F2RAB9ALMNA | |
| SCHEMBL8707197 | 0.74 | HTT (0.50) | EGFRGALR3RAB9ALMNAHTT | |
| SCHEMBL9038109 | 0.74 | HTT (0.50) | EGFRGALR3RAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | disclosed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |