Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025185 | 0.90 | PRMT1 (0.48) | EGFRTP53MAPTHTTLMNA | |
| SCHEMBL8026802 | 0.89 | CDK1 (0.50) | EGFRMAPK1PDE5AHTTLMNA | |
| SCHEMBL8024781 | 0.87 | HTT (0.55) | EGFRTP53MAPK1PDE5AMAPT | |
| SCHEMBL8014589 | 0.79 | SLC6A4 (0.41) | EGFRTP53CNR1CNR2MAPT | |
| SCHEMBL9039173 | 0.78 | CNR1 (0.48) | TP53CNR1CNR2HTTLMNA | |
| SCHEMBL8025396 | 0.77 | CDK1 (0.50) | EGFRMAPK1HTTLMNA | |
| SCHEMBL9037270 | 0.77 | GALR3 (0.59) | EGFRTP53MAPK1MAPTHTT | |
| SCHEMBL8401676 | 0.76 | RAB9A (0.57) | TP53HTTLMNAHSD17B10 | |
| SCHEMBL29176418 | 0.76 | HTT (0.43) | EGFRPDE5AMAPTHTTLMNA | |
| SCHEMBL8485751 | 0.75 | HTT (0.51) | EGFRTP53MAPK1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |