Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL8025514 | 1.00 | LTA4H (0.46) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Lysine SCHEMBL7792976 | 0.97 | LTA4H (0.45) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Lysine SCHEMBL7792973 | 0.97 | LTA4H (0.45) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Phenylacetic Acid SCHEMBL7802699 | 0.97 | LTA4H (0.45) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Phenylacetic Acid SCHEMBL7802702 | 0.97 | LTA4H (0.45) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Ornithine Aketoglutarate SCHEMBL7800245 | 0.95 | LTA4H (0.49) | LTA4HITGB3ITGA2BPTGESALOX5 | |
| Ornithine SCHEMBL7800241 | 0.95 | LTA4H (0.49) | LTA4HITGB3ITGA2BPTGESALOX5 | |
| Lysine SCHEMBL7798394 | 0.94 | LTA4H (0.44) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Lysine SCHEMBL7798391 | 0.94 | LTA4H (0.44) | LTA4HLTB4RLTB4R2ITGB3ITGA2B | |
| Phenylacetic Acid SCHEMBL7802615 | 0.93 | LTB4R (0.44) | LTA4HLTB4RLTB4R2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |