Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8025532 | 1.00 | CYP2C9 (0.33) | CYP2C9GRIK1CYP2C19HIF1ACYP1A2 | |
| Lysine SCHEMBL8041442 | 0.88 | GSR (0.43) | — | |
| Lysine SCHEMBL8041446 | 0.88 | GSR (0.43) | — | |
| Cyclohexylamine SCHEMBL7802316 | 0.86 | CYP2C9 (0.36) | CYP2C9CYP2C19HIF1ACYP1A2CYP3A4 | |
| Cyclohexylamine SCHEMBL7793152 | 0.84 | CYP2C9 (0.40) | CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6 | |
| Cyclohexylamine SCHEMBL8025661 | 0.83 | GRIK1 (0.40) | CYP2C9GRIK1GRIK2 | |
| Cyclohexylamine SCHEMBL8025659 | 0.83 | GRIK1 (0.40) | CYP2C9GRIK1GRIK2 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037276 | 0.81 | ALDH5A1 (0.41) | GRIK1KIF11GRIK2 | |
| 4-Hydroxybenzaldehyde SCHEMBL8037281 | 0.81 | ALDH5A1 (0.41) | GRIK1KIF11GRIK2 | |
| Benzaldehyde SCHEMBL8035694 | 0.81 | KIF11 (0.42) | GRIK1KIF11GRIK2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |