Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126603 | 0.86 | TDP1 (0.49) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL3209414 | 0.86 | TDP1 (0.49) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL8025820 | 0.83 | PLA2G2D (0.42) | PLA2G2DALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL20480721 | 0.81 | PTGER4 (0.43) | TDP1PLA2G2DALDH1A1NPC1MAPT | |
| SCHEMBL9775850 | 0.80 | TDP1 (0.59) | TDP1SMN1; SMN2PTGER4PTGER3PTGER2 | |
| SCHEMBL28812891 | 0.76 | PTGER4 (0.42) | TDP1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL3878972 | 0.74 | PTGER3 (0.47) | TDP1ALDH1A1PTGER4PTGER3PTGER2 | |
| SCHEMBL9276412 | 0.74 | PTGER1 (0.47) | PLA2G2DALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL9454885 | 0.73 | LMNA (0.37) | TDP1PLA2G2DALDH1A1PTGER4PTGER3 | |
| Oxamyl SCHEMBL29152631 | 0.73 | ACHE (0.32) | TDP1ALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069409-A1 | METHODS FOR UPREGULATING AND/OR MODULATING KGF PRODUCTION AND INCREASING RECEPTIVITY OF KERATINOCYTES TO KGF | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |