Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498322 | 0.88 | BAZ2B (0.56) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| SCHEMBL8036143 | 0.85 | MAPKAPK2 (0.48) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| SCHEMBL8025879 | 0.76 | MAPKAPK2 (0.59) | MAPKAPK2BAZ2BSIRT1MAPKAPK5 | |
| SCHEMBL7508089 | 0.75 | KDM4E (0.51) | MAPKAPK2KDRBAZ2BSIRT1MEN1 | |
| SCHEMBL8035773 | 0.75 | KDR (0.53) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| SCHEMBL10579013 | 0.74 | MAPKAPK2 (0.52) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| SCHEMBL10579154 | 0.74 | MAPKAPK2 (0.52) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| SCHEMBL10579020 | 0.74 | MAPKAPK2 (0.52) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| Hydrochloric Acid SCHEMBL10574826 | 0.74 | MAPKAPK2 (0.51) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR | |
| Hydrochloric Acid SCHEMBL10574828 | 0.74 | MAPKAPK2 (0.51) | MAPKAPK2L3MBTL1TRPA1TRPV1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |