Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 13/20 | 0.54 |
| ▸ | RARB | P10826 | 13/20 | 0.54 |
| ▸ | RARG | P13631 | 12/20 | 0.54 |
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026160 | 0.94 | RARA (0.56) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8030269 | 0.88 | RARA (0.53) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8026773 | 0.87 | RARA (0.56) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8026585 | 0.86 | RARA (0.55) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8031535 | 0.85 | RARA (0.53) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8026150 | 0.83 | RARA (0.52) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8025901 | 0.82 | RXRA (0.52) | RARARARBRARGRXRARXRB | |
| SCHEMBL8015897 | 0.77 | RARA (0.61) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7413570 | 0.77 | RARB (0.61) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8026158 | 0.76 | RXRA (0.54) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | claimed |
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |