Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.68 |
| ▸ | PPARG | P37231 | 7/20 | 0.68 |
| ▸ | PPARD | Q03181 | 7/20 | 0.68 |
| ▸ | PPARA | Q07869 | 7/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TLR2 | O60603 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | FABP4 | P15090 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Behenic Acid SCHEMBL8855897 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL8855969 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL29634265 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL5147676 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Biphenyl SCHEMBL28521917 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL5146634 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL8855788 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL29634079 | 1.00 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL9840415 | 0.98 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL11768047 | 0.98 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297357-B2 | Temperature-sensitive indicator | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2025-05-13 | — | — | US | disclosed |
| EP-3344468-B1 | COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2025-03-05 | — | — | EP | disclosed |
| US-11608440-B2 | Compound for use in colour change compositions | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2023-03-21 | — | — | US | disclosed |
| US-20220135804-A1 | Temperature-Sensitive Indicator | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135804-A1 | Temperature-Sensitive Indicator | NCS1, TREH, NEFM | GPR84 3162/4885PPARG 3185/4885PPARD 3800/4885 |
| US-11608440-B2 | Compound for use in colour change compositions | TYR, F12, SCO2 | GPR84 2707/4885PPARG 3523/4885PPARD 4405/4885 |
| US-12297357-B2 | Temperature-sensitive indicator | NCS1, TREH, NEFM | GPR84 3162/4885PPARG 3185/4885PPARD 3800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.