SCHEMBL8026205

SCHEMBL8026205

c1ccc2c(c1)OCCOCCOCCOCCOCCOCCOCCOCCOCCOc1ccccc1OCCOCCOCCOCCOCCOCCOCCOCCOCCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
CRHBP P24387 2/20 1.00
CRHR2 Q13324 2/20 1.00
HTT P42858 2/20 1.00
ITGB2 P05107 1/20 0.82
ICAM1 P05362 1/20 0.82
ITGAL P20701 1/20 0.82
GAA P10253 2/20 0.65
ABCG2 Q9UNQ0 1/20 0.55
KDM4E B2RXH2 3/20 0.55
MAPT P10636 5/20 0.54
BLM P54132 1/20 0.54
NPSR1 Q6W5P4 1/20 0.50
KMT2A Q03164 1/20 0.42
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687476 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL676131 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL35765 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL35679 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505745 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505395 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL23658043 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL10425464 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL603441 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL16076325 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6069207-A ANIONIC POLYMERIZATE OF AT LEAST TWO MONOMERS IN PRESENCE OF AT LEAST ONE ALKALI OR ALKALINE EARTH METAL, MONO- OR DIFUNCTIONAL INITIATOR AND LIGAND SELECTED FROM NONNITROGENOUS MACROCYCLIC COMPLEXANT OR ALKALI METAL ALCOHOLATE ELF ATOCHEM S.A. (FR) 2000-05-30 US disclosed
US-5977261-A BLOCK POLYMERS ELF ATOCHEM S.A. (FR) 1999-11-02 US disclosed
US-5670591-A IN PRESENCE OF A ALKALI(METAL) INITIATOR AND A LIGAND ELF ATOCHEM S.A. (FR) 1997-09-23 US disclosed
US-5561207-A USING COORDINATION CATALYST ELF ATOCHEM S.A. (FR) 1996-10-01 US disclosed
EP-0463947-B1 Process for the preparation of sulphur containing acrylic compounds ATOCHEM ELF SA (FR) 1995-10-25 EP disclosed
EP-0668297-A1 Living statistic (meth)acrylat copolymers, copolymers prepared from these living copolymers, and process for preparing these copolymers by anionic copolymerisation ELF ATOCHEM S.A. (FR) 1995-08-23 EP disclosed
EP-0274318-B1 PROCESS FOR THE ANIONIC POLYMERIZATION OF ACRYLIC MONOMERS AND VINYL COMONOMERS ELF ATOCHEM S.A. (FR) 1992-04-08 EP disclosed
EP-0463947-A1 Process for the preparation of sulphur containing acrylic compounds ELF ATOCHEM S.A. (FR) 1992-01-02 EP disclosed
US-4927703-A Process for the anionic polymerization of acrylic monomers and optionally of vinyl comonomers NORSOLOR (FR) 1990-05-22 US disclosed
EP-0274318-A2 Process for the anionic polymerization of acrylic monomers and vinyl comonomers ELF ATOCHEM S.A. (FR) 1988-07-13 EP disclosed