SCHEMBL676131

SCHEMBL676131

c1ccc2c(c1)OCCOCCOCCOc1ccccc1OCCOCCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
CRHBP P24387 2/20 1.00
CRHR2 Q13324 2/20 1.00
HTT P42858 2/20 1.00
ITGB2 P05107 1/20 0.82
ICAM1 P05362 1/20 0.82
ITGAL P20701 1/20 0.82
GAA P10253 2/20 0.65
ABCG2 Q9UNQ0 1/20 0.55
KDM4E B2RXH2 3/20 0.55
MAPT P10636 5/20 0.54
BLM P54132 1/20 0.54
NPSR1 Q6W5P4 1/20 0.50
KMT2A Q03164 1/20 0.42
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687476 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL35765 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL35679 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505745 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505395 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL23658043 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL10425464 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL603441 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL8026205 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL16076325 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170299566-A1 Reagents For Oxidizer-Based Chemical Detection MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2017-10-19 US claimed
US-9588095-B2 Reagents for oxidizer-based chemical detection MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-03-07 US claimed
US-20150004710-A1 REAGENTS FOR OXIDIZER-BASED CHEMICAL DETECTION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-01-01 US claimed
EP-3808425-B1 METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2025-08-13 EP disclosed
US-11827743-B2 Polymers having stable cationic pendant groups for use as anion exchange membranes UNIVERSITY OF DELAWARE (US) 2023-11-28 US disclosed
US-11827743-B2 Polymers having stable cationic pendant groups for use as anion exchange membranes UNIVERSITY OF DELAWARE (US) 2023-11-28 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
US-20220393174-A1 CROWN ETHERS AS ADDITIVES FOR SILICON-BASED LI-ION BATTERIES ENEVATE CORPORATION 2022-12-08 US disclosed
US-11237143-B2 Reagents for oxidizer-based chemical detection MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-02-01 US disclosed
US-20070137519-A1 Preservative Solution BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-06-21 US disclosed
US-20070137519-A1 Preservative Solution BROTHER KOGYO KABUSHIKI KAISHA (JP) 2007-06-21 US disclosed
US-7211373-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2007-05-01 US disclosed
US-7211373-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2007-05-01 US disclosed
US-20070004821-A1 Condensation-crosslinked dental material hardening to dimensionally stable casts KETTENBACH GMBH & CO. KG 2007-01-04 US disclosed
US-20070004821-A1 Condensation-crosslinked dental material hardening to dimensionally stable casts KETTENBACH GMBH & CO. KG 2007-01-04 US disclosed
EP-1738737-A1 Dimensionally stable articles from cured condensation-crosslinked dental material Kettenbach GmbH & CO. KG (DE) 2007-01-03 EP disclosed
US-4110360-A FROM AN ALDEHYDE, ACID HALIDE AND CYANIDE SHELL OIL COMPANY (US) 1978-08-29 US disclosed
US-4110363-A FROM AN ALDEHYDE, ACID HALIDE AND CYANIDE, MACROCYCLIC POLYETHER CATALYST SHELL OIL COMPANY (US) 1978-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 LMNA 1748/4885SMN1; SMN2 2006/4885CRHBP 3287/4885
US-20070004821-A1 Condensation-crosslinked dental material hardening to dimensionally stable casts SMCHD1, SMC1A, SMC2 LMNA 550/4885SMN1; SMN2 2843/4885CRHBP 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.