SCHEMBL8026256

SCHEMBL8026256

CCCOc1ccc2cccc(CCCC(N)=O)c2c1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 20/20 0.73
MTNR1B P49286 11/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8690256 0.87 MTNR1A (0.67) MTNR1AMTNR1B
SCHEMBL8021685 0.85 MTNR1A (0.60) MTNR1AMTNR1B
SCHEMBL5130356 0.85 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7023879 0.83 MTNR1A (0.85) MTNR1AMTNR1B
SCHEMBL8021299 0.82 MTNR1A (0.68) MTNR1AMTNR1B
SCHEMBL27876475 0.82 MTNR1A (0.66) MTNR1AMTNR1B
SCHEMBL8570503 0.81 MTNR1A (0.92) MTNR1AMTNR1B
SCHEMBL8031436 0.81 MTNR1A (0.61) MTNR1AMTNR1B
SCHEMBL8571135 0.80 MTNR1A (0.66) MTNR1AMTNR1B
SCHEMBL27859955 0.80 MTNR1A (0.88) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745584-B1 Arylalkyl(thio) carboxamides compounds with affinity for melatonine receptors, processes for their preparation and pharmaceutical compositions containing them ADIR (FR) 2000-01-05 EP disclosed
EP-0745584-A1 Arylalkyl(thio) carboxamides compounds with affinity for melatonine receptors, processes for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1996-12-04 EP disclosed