Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.92 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130356 | 0.96 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL124740 | 0.92 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL8689984 | 0.85 | MTNR1A (0.81) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL8575303 | 0.85 | MTNR1A (0.84) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL8570966 | 0.84 | MTNR1A (0.86) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL8021722 | 0.83 | MTNR1A (0.69) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL4749238 | 0.83 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL31558766 | 0.83 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL30449230 | 0.83 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL29593962 | 0.82 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CHTR2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760071-A | AN UREA OR THIOUREA COMPOUNDS FOR TREATING MELATONINERGIC SYSTEM DISORDER, SLEEP DISORDER | ADIR ET COMPAGNIE (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5731352-A | THERAPY FOR DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-03-24 | — | — | US | disclosed |