Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032287 | 0.75 | MAOA (0.42) | MAOA | |
| SCHEMBL8024307 | 0.72 | MAOA (0.40) | MAOAMKNK2 | |
| SCHEMBL8034390 | 0.72 | MAOA (0.40) | MAOA | |
| SCHEMBL15222063 | 0.72 | MAOA (0.40) | MAOA | |
| SCHEMBL10098870 | 0.71 | NTRK1 (0.34) | NTRK1 | |
| SCHEMBL10297757 | 0.71 | NTRK1 (0.34) | NTRK1 | |
| SCHEMBL31569021 | 0.70 | GPR119 (0.39) | — | |
| SCHEMBL31569123 | 0.70 | GPR119 (0.39) | — | |
| SCHEMBL12969035 | 0.70 | MAOA (0.39) | MAOA | |
| SCHEMBL8030002 | 0.69 | MAOA (0.47) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |