Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573693 | 0.81 | PGR (0.44) | MAPTCYP2A6HRH3PGR | |
| SCHEMBL7806512 | 0.81 | LOXL2 (0.60) | LOXL2CYP2A6AGXTHTR1AHTR2B | |
| SCHEMBL11107879 | 0.80 | LOXL2 (0.55) | MAPTLOXL2AGXTHTR1AHTR2B | |
| SCHEMBL22113436 | 0.79 | HTR2B (0.73) | HTR1AHTR2BDRD2 | |
| SCHEMBL11612003 | 0.79 | LOXL2 (0.53) | MAPTLOXL2AGXTHTR1AHTR2B | |
| SCHEMBL10368738 | 0.79 | LOXL2 (0.53) | MAPTLOXL2AGXTHTR1AHTR2B | |
| SCHEMBL11616186 | 0.79 | LOXL2 (0.53) | MAPTLOXL2CYP2A6AGXTHTR1A | |
| SCHEMBL29087527 | 0.79 | LOXL2 (0.53) | LOXL2CYP2A6AGXTHTR1AHTR2B | |
| SCHEMBL7389419 | 0.78 | HRH3 (0.44) | MAPTCYP2A6HRH3 | |
| SCHEMBL14075637 | 0.77 | LOXL2 (0.69) | LOXL2CYP2A6AGXTHTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |