Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.60 |
| ▸ | CES1 | P23141 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604299 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27388550 | 0.85 | KMT2A (0.64) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11352927 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8884550 | 0.84 | ATM (0.67) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6570860 | 0.84 | KMT2A (0.62) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6777037 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9492603 | 0.83 | ALDH1A1 (0.76) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6835143 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6959553 | 0.82 | KMT2A (0.69) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL432613 | 0.82 | KMT2A (0.69) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000055179-A1 | NOVEL PHOSPHATE AND THIOPHOSPHATE PROTECTING GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |