SCHEMBL432613

SCHEMBL432613

NNC(=O)c1cccc([N+](=O)[O-])c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.69
MEN1 O00255 2/20 0.69
TSHR P16473 2/20 0.67
CES2 O00748 1/20 0.66
CES1 P23141 1/20 0.66
TP53 P04637 1/20 0.64
THRA P10827 1/20 0.62
POLB P06746 2/20 0.62
MAPT P10636 1/20 0.62
BLM P54132 1/20 0.62
ALDH1A1 P00352 5/20 0.62
HPGD P15428 3/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
LMNA P02545 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PRSS1 P07477 1/20 0.58
PRSS2 P07478 1/20 0.58
PRSS3 P35030 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30163119 1.00 KMT2A (0.69) KMT2AMEN1TSHRCES2CES1
SCHEMBL2830307 0.86 ALDH1A1 (0.63) KMT2AMEN1THRAMAPTALDH1A1
SCHEMBL11060904 0.86 KMT2A (0.73) KMT2AMEN1TSHRCES2CES1
SCHEMBL29508878 0.84 KMT2A (0.71) KMT2AMEN1TSHRCES2CES1
SCHEMBL297043 0.84 KMT2A (0.71) KMT2AMEN1TSHRCES2CES1
SCHEMBL10604299 0.83 ALDH1A1 (0.66) KMT2AMEN1TSHRCES2CES1
SCHEMBL10790549 0.83 TSHR (0.68) KMT2AMEN1TSHRCES2CES1
SCHEMBL31216547 0.83 TSHR (0.68) KMT2AMEN1TSHRCES2CES1
SCHEMBL8298064 0.83 TSHR (0.62) KMT2AMEN1TSHRCES2CES1
Hydrochloric Acid SCHEMBL2045145 0.83 KMT2A (0.69) KMT2AMEN1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480848-B Electric and heat conducting silver adhesive for chip bonding and preparation method thereof 深圳市撒比斯科技有限公司 2021-07-23 CN claimed
CN-112480848-A Electric and heat conducting silver adhesive for chip bonding and preparation method thereof 深圳市撒比斯科技有限公司 2021-03-12 CN claimed
US-20110178317-A1 MEDICINAL APPLICATIONS OF BENZOIC ACID HYDRAZONES SYNTHESIZED ON THE BASIS OF STEROIDAL TIGOGENIN SHELAR, ASHOK RANGANATH (IN) 2011-07-21 US claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 US claimed
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US claimed
US-5527920-A Economical manufacturing process for 1,2,3-triazoles SYNPHAR LABORATORIES, INC. (CA) 1996-06-18 US claimed
JP-3258000-A None JP disclosed
JP-3257999-A None JP disclosed
US-12605794-B2 Flux and solder paste SENJU METAL INDUSTRY CO., LTD. (JP) 2026-04-21 US disclosed
US-12515282-B2 Flux and method for producing electronic component SENJU METAL INDUSTRY CO., LTD. (JP) 2026-01-06 US disclosed
EP-4332257-B1 FLUX AND SOLDER PASTE SENJU METAL INDUSTRY CO (JP) 2025-10-15 EP disclosed
US-20250256363-A1 FLUX AND METHOD FOR PRODUCING ELECTRONIC COMPONENT SENJU METAL INDUSTRY CO., LTD. (JP) 2025-08-14 US disclosed
US-4243739-A HYDRAZIDE FUJI PHOTO FILM CO., LTD. (JP) 1981-01-06 US disclosed
US-4179439-A Rifamycins and method for their preparation INTREPRINDEREA DE ANTIBIOTICE IASI (RO) 1979-12-18 US disclosed
US-4125704-A Phenyl-substituted rubidazone analogs SRI INTERNATIONAL (US) 1978-11-14 US disclosed
US-4016162-A BRONCHODILATORS GRUPPO LEPETIT S.P.A. (IT) 1977-04-05 US disclosed
US-3941749-A FILMS, FILAMENTS WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-03-02 US disclosed
US-3933737-A SULFUR-CONTAINING ORGANOTIN COMPOUNDS AND NON-SULFUR-CONTAINING ORGANOTIN COMPOUNDS KABEL-UND METALLWERKE GUTEHOFFNUNGSHUTTE AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 KMT2A 2064/4885MEN1 2427/4885TSHR 2028/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 KMT2A 2064/4885MEN1 2427/4885TSHR 2028/4885
US-12605794-B2 Flux and solder paste RIOK2, TRA2B, BAG2 KMT2A 3348/4885MEN1 64/4885TSHR 4395/4885
US-20110178317-A1 MEDICINAL APPLICATIONS OF BENZOIC ACID HYDRAZONES SYNTHESIZED ON THE BASIS OF STEROIDAL TIGOGENIN CYP17A1, CYP51A1, HSD17B7 KMT2A 1699/4885MEN1 3959/4885TSHR 2849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.