Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633366 | 0.84 | MAPT (0.48) | RIPK1ACP1ABCG2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3203107 | 0.84 | RIPK1 (0.51) | RIPK1ACP1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL8028354 | 0.79 | HDAC6 (0.44) | HDAC6ALDH1A1CYP3A4CYP2C19CYP19A1 | |
| SCHEMBL8033087 | 0.79 | ALDH1A1 (0.46) | HDAC6ALDH1A1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL9642062 | 0.75 | RIPK1 (0.55) | RIPK1KCNJ1ACP1HDAC6ALDH1A1 | |
| SCHEMBL31215568 | 0.75 | RIPK1 (0.52) | RIPK1ACP1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL201882 | 0.75 | RIPK1 (0.52) | RIPK1ACP1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL3910308 | 0.75 | AKR1B1 (0.46) | RIPK1ACP1HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL8027000 | 0.74 | RIPK1 (0.58) | RIPK1KCNJ1KCNH2ABCG2ALDH1A1 | |
| SCHEMBL30370212 | 0.74 | APP (0.54) | ALDH1A1SMN1; SMN2CYP3A4MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |