Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.49 |
| ▸ | ACE | P12821 | 8/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027100 | 1.00 | MME (0.49) | MMEACECA2CA4SUCNR1 | |
| SCHEMBL8453835 | 0.88 | MME (0.61) | MMEACECA2CA4 | |
| SCHEMBL8028702 | 0.88 | MME (0.61) | MMEACECA2CA4 | |
| SCHEMBL8028700 | 0.88 | MME (0.61) | MMEACECA2CA4 | |
| SCHEMBL27464505 | 0.83 | MME (0.44) | MMEACECA2ALDH1A1KDM4E | |
| SCHEMBL8027302 | 0.83 | MME (0.44) | MMEACECA2ALDH1A1KDM4E | |
| SCHEMBL8027297 | 0.83 | MME (0.44) | MMEACECA2ALDH1A1KDM4E | |
| SCHEMBL8451445 | 0.82 | MME (0.36) | MMEACEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8026913 | 0.81 | MME (0.43) | MMEACEALDH1A1 | |
| SCHEMBL8026918 | 0.81 | MME (0.43) | MMEACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |