Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.61 |
| ▸ | ACE | P12821 | 9/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028700 | 1.00 | MME (0.61) | MMEACECA2CA4SMN1; SMN2 | |
| SCHEMBL8453835 | 1.00 | MME (0.61) | MMEACECA2CA4SMN1; SMN2 | |
| SCHEMBL8027100 | 0.88 | MME (0.49) | MMEACECA2CA4 | |
| SCHEMBL8027105 | 0.88 | MME (0.49) | MMEACECA2CA4 | |
| SCHEMBL8033718 | 0.81 | MME (0.56) | MMEACECA2SMN1; SMN2 | |
| SCHEMBL8033722 | 0.81 | MME (0.56) | MMEACECA2SMN1; SMN2 | |
| SCHEMBL8452172 | 0.79 | MME (0.45) | MMEACECA2SMN1; SMN2 | |
| SCHEMBL8027559 | 0.78 | MME (0.53) | MMEACECA2SMN1; SMN2 | |
| SCHEMBL8027558 | 0.78 | MME (0.53) | MMEACECA2SMN1; SMN2 | |
| SCHEMBL8032885 | 0.78 | MME (0.88) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |