Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.36 |
| ▸ | ACE | P12821 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452172 | 0.85 | MME (0.45) | MMEACECYP2D6CYP2C19 | |
| SCHEMBL8027100 | 0.82 | MME (0.49) | MMEACEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8027105 | 0.82 | MME (0.49) | MMEACEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27464505 | 0.78 | MME (0.44) | MMEACEKDM4EALDH1A1 | |
| SCHEMBL8027297 | 0.78 | MME (0.44) | MMEACEKDM4EALDH1A1 | |
| SCHEMBL8027302 | 0.78 | MME (0.44) | MMEACEKDM4EALDH1A1 | |
| SCHEMBL8452086 | 0.76 | MME (0.46) | MMEACEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8026913 | 0.76 | MME (0.43) | MMEACEALDH1A1 | |
| SCHEMBL27464506 | 0.76 | MME (0.43) | MMEACEALDH1A1 | |
| SCHEMBL8026918 | 0.76 | MME (0.43) | MMEACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |