Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.58 |
| ▸ | MME | P08473 | 10/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463686 | 0.95 | ACE (0.52) | ACEMMECPA1ACE2GPR34 | |
| SCHEMBL8027188 | 0.92 | ACE (0.67) | ACEMMECPA1ACE2 | |
| SCHEMBL8017386 | 0.92 | MME (0.63) | ACEMMECPA1ACE2GPR34 | |
| SCHEMBL8017382 | 0.92 | MME (0.63) | ACEMMECPA1ACE2GPR34 | |
| SCHEMBL8028610 | 0.91 | ACE (0.68) | ACEMMECPA1ACE2 | |
| SCHEMBL27446261 | 0.91 | MME (0.70) | ACEMMECPA1ACE2GPR34 | |
| SCHEMBL8030172 | 0.91 | MME (0.70) | ACEMMECPA1ACE2GPR34 | |
| SCHEMBL8028778 | 0.90 | MME (0.52) | ACEMMECPA1ACE2GPR34 | |
| SCHEMBL27464504 | 0.88 | ACE (0.60) | ACEMME | |
| SCHEMBL27446254 | 0.87 | ACE (0.55) | ACEMMEGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |