Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.60 |
| ▸ | MME | P08473 | 8/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.42 |
| ▸ | MC5R | P33032 | 2/20 | 0.42 |
| ▸ | MC3R | P41968 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027188 | 0.95 | ACE (0.67) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL27463686 | 0.92 | ACE (0.52) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL27464503 | 0.89 | TACR1 (0.57) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL8449552 | 0.88 | ACE (0.50) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL8027149 | 0.88 | ACE (0.58) | ACEMME | |
| SCHEMBL27446254 | 0.87 | ACE (0.55) | ACEMMETACR1CTSBPTGES | |
| SCHEMBL8029487 | 0.85 | MME (0.81) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL8026927 | 0.85 | MME (0.81) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL8016985 | 0.85 | MME (0.81) | ACEMMETACR1CTSLCTSB | |
| SCHEMBL8032641 | 0.85 | MME (0.81) | ACEMMETACR1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |