Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027201 | 1.00 | MME (0.51) | MMEACEL3MBTL1MMP8PSMB1 | |
| SCHEMBL27442620 | 0.94 | TP53 (0.48) | MMEACEMMP8PSMB1PSMB5 | |
| SCHEMBL8033727 | 0.89 | MME (0.62) | MMEACEL3MBTL1PSMB1PSMB5 | |
| SCHEMBL8033733 | 0.89 | MME (0.62) | MMEACEL3MBTL1PSMB1PSMB5 | |
| SCHEMBL8017424 | 0.88 | MME (0.57) | MMEACEL3MBTL1LPAR1PTPN1 | |
| SCHEMBL8017421 | 0.88 | MME (0.57) | MMEACEL3MBTL1LPAR1PTPN1 | |
| SCHEMBL8028768 | 0.86 | MME (0.58) | MMEACECPA1ACE2 | |
| SCHEMBL8028772 | 0.86 | MME (0.58) | MMEACECPA1ACE2 | |
| SCHEMBL8017258 | 0.86 | MME (0.52) | MMEACEL3MBTL1MMP8CPA1 | |
| SCHEMBL8017263 | 0.86 | MME (0.52) | MMEACEL3MBTL1MMP8CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |