Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.62 |
| ▸ | ACE | P12821 | 8/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033733 | 1.00 | MME (0.62) | MMEACEPSMB1PSMB5PSMB2 | |
| SCHEMBL8027314 | 0.93 | MME (0.72) | MMEACE | |
| SCHEMBL8027310 | 0.93 | MME (0.72) | MMEACE | |
| SCHEMBL8027205 | 0.89 | MME (0.51) | MMEACEPSMB1PSMB5PSMB2 | |
| SCHEMBL8027201 | 0.89 | MME (0.51) | MMEACEPSMB1PSMB5PSMB2 | |
| SCHEMBL8027264 | 0.86 | ACE (0.74) | MMEACE | |
| SCHEMBL8027141 | 0.85 | MME (0.63) | MMEACE | |
| SCHEMBL8030332 | 0.85 | MME (0.68) | MMEACENPSR1PTPN1 | |
| SCHEMBL8030328 | 0.85 | MME (0.68) | MMEACENPSR1PTPN1 | |
| SCHEMBL8028768 | 0.84 | MME (0.58) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |