Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044076 | 0.80 | HSP90AA1 (0.35) | HSP90AA1P2RX7 | |
| SCHEMBL16399201 | 0.77 | — | — | |
| SCHEMBL3260151 | 0.73 | CHRNB2 (0.44) | KDM4EALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL7305076 | 0.73 | CYP19A1 (0.43) | KDM4EALDH1A1MAPTSNCAMAPK1 | |
| SCHEMBL5883850 | 0.72 | — | — | |
| SCHEMBL27858236 | 0.72 | — | — | |
| SCHEMBL27916645 | 0.72 | — | — | |
| SCHEMBL1416291 | 0.72 | — | — | |
| SCHEMBL13764327 | 0.72 | CA12 (0.48) | KDM4EALDH1A1MAPTSNCACA12 | |
| SCHEMBL27928341 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742153-A1 | PROTEIN AND PEPTIDE LIBRARIES | The General Hospital Corporation (US) | 2014-06-18 | — | — | EP | claimed |
| WO-2013019794-A1 | PROTEIN AND PEPTIDE LIBRARIES | THE GENERAL HOSPITAL CORPORATION (US) | 2013-02-07 | — | — | WO | claimed |
| EP-0974586-A1 | 2-amino-4-alkylamino-pyrimidine 3-oxydes and compositions containing same | L'OREAL (FR) | 2000-01-26 | — | — | EP | claimed |
| US-5929046-A | Pyrimidine and purine derivatives and their use in treating tumour cells | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-07-27 | — | — | US | claimed |
| EP-2742153-B1 | PROTEIN AND PEPTIDE LIBRARIES | MASSACHUSETTS GEN HOSPITAL (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20170198282-A1 | PROTEIN AND PEPTIDE LIBRARIES | THE GENERAL HOSPITAL CORPORATION (US) | 2017-07-13 | — | — | US | disclosed |
| CN-106496104-A | The synthetic method of 6 methylpyrimidine of medical intermediate 4 (allyloxy) 2 chlorine | 无锡乾浩生物医药有限公司 | 2017-03-15 | — | — | CN | disclosed |
| US-9422550-B2 | Protein and peptide libraries | THE GENERAL HOSPITAL CORPORATION (US) | 2016-08-23 | — | — | US | disclosed |
| US-20140234898-A1 | PROTEIN AND PEPTIDE LIBRARIES | THE GENERAL HOSPITAL CORPORATION (US) | 2014-08-21 | — | — | US | disclosed |
| EP-2742153-A1 | PROTEIN AND PEPTIDE LIBRARIES | The General Hospital Corporation (US) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013019794-A1 | PROTEIN AND PEPTIDE LIBRARIES | THE GENERAL HOSPITAL CORPORATION (US) | 2013-02-07 | — | — | WO | disclosed |
| EP-0974586-A1 | 2-amino-4-alkylamino-pyrimidine 3-oxydes and compositions containing same | L'OREAL (FR) | 2000-01-26 | — | — | EP | disclosed |
| US-5929046-A | Pyrimidine and purine derivatives and their use in treating tumour cells | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |