Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 18/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803047 | 0.87 | ESR1 (0.50) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL802620 | 0.84 | ESR1 (0.43) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL803020 | 0.79 | SLC22A8 (0.34) | KCNJ1KCNH2 | |
| SCHEMBL19433455 | 0.74 | KCNJ1 (0.66) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL803200 | 0.69 | ESR1 (0.62) | ESR1ESR2KCNJ1KCNH2ACHE | |
| SCHEMBL6830103 | 0.66 | ESR1 (1.00) | ESR1ESR2KCNJ1KCNH2ACHE | |
| SCHEMBL22644204 | 0.65 | ESR1 (0.43) | ESR1ESR2KCNJ1KCNH2 | |
| SCHEMBL803018 | 0.65 | PDK2 (0.31) | ESR1ESR2 | |
| SCHEMBL803204 | 0.65 | PARP10 (0.35) | — | |
| SCHEMBL18019265 | 0.65 | KCNJ1 (0.69) | KCNJ1KCNH2ACHESSTR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096795-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | LPXN, VCL, ACP3 | ESR1 1013/4885ESR2 2665/4885KCNJ1 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.