SCHEMBL803204

SCHEMBL803204

CCc1ccc2c(c1C)CCc1c-2ccc(-c2ccc(CP)cc2)c1C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.35
PARP11 Q9NR21 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803199 0.89 PARP10 (0.35) PARP10PARP11
SCHEMBL803020 0.82 SLC22A8 (0.34)
SCHEMBL802620 0.81 ESR1 (0.43)
SCHEMBL803030 0.75 PDCD1 (0.30)
SCHEMBL803052 0.72 ESR1 (0.44)
SCHEMBL803140 0.69 TDP2 (0.31)
SCHEMBL18806006 0.69 CD274 (0.34)
SCHEMBL20382359 0.67 PDCD1 (0.33)
SCHEMBL802741 0.65 ESR1 (0.49)
SCHEMBL17488389 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120069289-A1 LIQUID CRYSTAL DISPLAY LPXN, VCL, ACP3 PARP10 2238/4885PARP11 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.