Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746491 | 1.00 | RIPK1 (0.55) | RIPK1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL13003036 | 0.83 | RIPK1 (0.64) | RIPK1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL12435669 | 0.83 | RIPK1 (0.64) | RIPK1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL5163930 | 0.83 | RIPK1 (0.64) | RIPK1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL6829386 | 0.82 | NR3C2 (0.39) | RIPK1AOC3KDM4ETAAR1HIF1A | |
| SCHEMBL3196437 | 0.81 | RIPK1 (0.57) | RIPK1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL5046280 | 0.80 | TAAR1 (0.48) | RIPK1SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL6829522 | 0.80 | AOC3 (0.53) | AOC3KDM4E | |
| SCHEMBL13821544 | 0.80 | RIPK1 (0.47) | RIPK1LMNAAOC3KDM4EL3MBTL1 | |
| Bromide SCHEMBL29799767 | 0.78 | TAAR1 (0.46) | RIPK1SLC6A2SLC6A4SLC6A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213254-B | Beta-nitroketone and preparation method and application method thereof | 北京师范大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114213254-A | Beta-nitroketone, and preparation method and application method thereof | 北京师范大学 | 2022-03-22 | — | — | CN | disclosed |
| US-20110028562-A1 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2011-02-03 | — | — | US | disclosed |
| WO-2000058262-A1 | STEREOSPECIFIC METHOD FOR PREPARING TOMOXETINE AND INTERMEDIATES THEREOF | ELI LILLY AND COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |
| US-6008412-A | REACTING N-METHYL-3(R,S)-HYDROXY-3-PHENYLPROPYLAMINE WITH S-(+)-MANDELIC ACID; SALT FORMATION | ELI LILLY AND COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028562-A1 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | ACHE, CNR2, SCN1A | RIPK1 4703/4885LMNA 1620/4885AOC3 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.